Kniha Synthesis and antimicrobial activity of Phthalimide derivatives Shakir Saleem

Synthesis and antimicrobial activity of Phthalimide derivatives

Antimicrobial activity of new molecules

Jazyk: Angličtina
Väzba: Brožovaná
Dostupnosť: U vydavateľa na objednávku
Odosielame za 17-27 dní
48.47
A series of novel phthalimide derivatives (SV 1-8) have been synthesized and evaluated for antimicro...

Informácie o knihe

Jazyk
Angličtina
Väzba
Kniha - Brožovaná
Vydalo
2012
Stránok
108
EAN
9783845418384
Enbook ID
07083923
Hmotnosť
168
Rozmery
152 x 229 x 7

Kompletný popis

A series of novel phthalimide derivatives (SV 1-8) have been synthesized and evaluated for antimicrobial activity. The target compounds were prepared by fusion of glycine with phthalic anhydride at 150-155 şC to afford 2-(1, 3- dioxoisoindolin-2-yl) acetic acid. The compound 2-(1, 3-dioxoisoindolin-2-yl) acetic acid was treated with thionyl chloride in chloroform to afford 2-(1, 3-dioxoisoindolin-2-yl) acetyl chloride which was further treated with substituted phenols in presence of anhydrous potassium carbonate in dry acetone yielded the final compounds (SV1-8). The structures of the target compounds were characterized on the basis of their m.p., TLC, IR and 1H-NMR data. All the target compounds were evaluated for antibacterial and antifungal activity.

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