Structure-based Drug Discovery

Name: Structure-based Drug Discovery
Brand: Springer-Verlag New York Inc.
SKU: 9781402044069
Price: 105.93 EUR
Availability: InStock

Autor: Harren Jhoti, Andrew R. Leach

Jazyk:

Väzba: Pevná

Vydavateľ: Springer-Verlag New York Inc.

Dostupnosť: Skladom u dodávateľa v malom množstve

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105.93 €

Structure-based drug discovery methods have been transformed in the last 5-10 years and are now havi...

Informácie o knihe

Autor

Harren Jhoti, Andrew R. Leach

Jazyk

Angličtina

Väzba

Kniha - Pevná

Vydalo

2006

Stránok

250

EAN

9781402044069

ISBN

1402044062

Enbook ID

01416560

Vydavateľ

Springer-Verlag New York Inc.

Hmotnosť

542

Rozmery

166 x 244 x 22

Kompletný popis

Structure-based drug discovery methods have been transformed in the last 5-10 years and are now having a major impact on the discovery of new drugs. Some of the most exciting developments in the field, such as Fragment-based methods, are described in this book.§The book describes the latest developments in technologies that can be used to obtain the 3-D structures including the high profile structural genomics approaches being utilised worldwide. The use of 3-D protein structures in new, Fragment-based, approaches to drug discovery are described in some detail. This book includes experimental approaches using X-ray crystallography and NMR for Fragment-based screening as well as other biophysical methods for studying protein/ligand interactions. In addition, developments in computational chemistry methodology are covered together with an assessment of practical applications.

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