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Specificity, Function, and Development of NK Cells

Name: Specificity, Function, and Development of NK Cells
Brand: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
SKU: 9783642468612
Price: 99.88 EUR
Availability: InStock

NK Cells: The Effector Arm of Innate Immunity

Autor: Marco Colonna, Klas Kärre

Jazyk:

Väzba: Brožovaná

Vydavateľ: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG

Dostupnosť: Skladom u dodávateľa

Odosielame za 8-11 dní

99.88 €

Our understanding of the function of natural killer (NK) cells has dramatically changed in recent ye...

Informácie o knihe

Autor

Marco Colonna, Klas Kärre

Jazyk

Angličtina

Väzba

Kniha - Brožovaná

Vydalo

2012

Stránok

248

EAN

9783642468612

ISBN

3642468616

Enbook ID

07110297

Vydavateľ

Springer-Verlag Berlin and Heidelberg GmbH & Co. KG

Hmotnosť

406

Rozmery

155 x 235 x 15

Kompletný popis

Our understanding of the function of natural killer (NK) cells has dramatically changed in recent years. The discovery of NK receptors specific for MHC class I molecules, and the study of the role of co-stimulatory and adhesion molecules have led to an understanding of how NK cells recognize tumor and virally infected cells that have lost expression of MHC class I molecules or have altered distribution of normal cell surface molecules. Such recognition events lead to intracellular signals which can be either stimulatory or inhibitory. This book provides an insight into how NK cells develop, how they learn to distinguish altered cells from normal cells, and into their biological role in controlling infections and tumors.