Kniha Screening Angela Dean

Screening

Methods for Experimentation in Industry, Drug Discovery, and Genetics

Jazyk: Angličtina
Väzba: Pevná
Dostupnosť: Skladom u dodávateľa v malom množstve
Odosielame za 13-18 dní
106.19
The process of discovery in science and technology may require investigation of a large number of fe...

Informácie o knihe

Jazyk
Angličtina
Väzba
Kniha - Pevná
Vydalo
2006
Stránok
332
EAN
9780387280134
ISBN
0387280138
Enbook ID
01381441
Hmotnosť
1480
Rozmery
155 x 235 x 25

Kompletný popis

The process of discovery in science and technology may require investigation of a large number of features, such as factors, genes or molecules. In Screening, statistically designed experiments and analyses of the resulting data sets are used to identify efficiently the few features that determine key properties of the system under study.§§This book brings together accounts by leading international experts that are essential reading for those working in fields such as industrial quality improvement, engineering research and development, genetic and medical screening, drug discovery, and computer simulation of manufacturing systems or economic models. Our aim is to promote cross-fertilization of ideas and methods through detailed explanations, a variety of examples and extensive references. §§Topics cover both physical and computer simulated experiments. They include screening methods for detecting factors that affect the value of a response or its variability, and for choosing between various different response models. Screening for disease in blood samples, for genes linked to a disease and for new compounds in the search for effective drugs are also described. Statistical techniques include Bayesian and frequentist methods of data analysis, algorithmic methods for both the design and analysis of experiments, and the construction of fractional factorial designs and orthogonal arrays.§§The material is accessible to graduate and research statisticians, and to engineers and chemists with a working knowledge of statistical ideas and techniques. It will be of interest to practitioners and researchers who wish to learn about useful methodologies from within their own area as well as methodologies that can be translated from one area to another.

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