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Randomization in Clinical Trials

Theory and Practice

Autor: William F. Rosenberger, John M. Lachin

Jazyk:

Väzba: Pevná

Vydavateľ: John Wiley & Sons Inc

Dostupnosť: 50 % šanca

Prehľadáme celý svet

177.97 €

A unique overview that melds the concepts of conditional probability and stochastic processes into r...

Informácie o knihe

Autor

William F. Rosenberger, John M. Lachin

Jazyk

Angličtina

Väzba

Kniha - Pevná

Vydalo

2002

Stránok

288

EAN

9780471236269

ISBN

0471236268

Enbook ID

04888843

Vydavateľ

John Wiley & Sons Inc

Hmotnosť

572

Rozmery

168 x 243 x 22

Kompletný popis

A unique overview that melds the concepts of conditional probability and stochastic processes into real-life applications The role of randomization techniques in clinical trials has become increasingly important. This comprehensive guide combines both the applied aspects of randomization in clinical trials with a probabilistic treatment of properties of randomization. Taking an unabashedly non-Bayesian and nonparametric approach to inference, the book focuses on the linear rank test under a randomization model, with added discussion on likelihood-based inference as it relates to sufficiency and ancillarity. Developments in stochastic processes and applied probability are also given where appropriate. Intuition is stressed over mathematics, but not without a clear development of the latter in the context of the former. Providing a consolidated review of the field, the book includes relevant and practical discussions of: The benefits of randomization in terms of reduction of bias Randomization as a basis for inference Covariate-adaptive and response-adaptive randomization Current philosophies, controversies, and new developments With ample problem sets, theoretical exercises, and short computer simulations using SAS, Randomization in Clinical Trials: Theory and Practice is equally useful as a standard textbook in biostatistics graduate programs as well as a reliable reference for biostatisticians in practice.

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Randomization in Clinical Trials

Theory and Practice

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