Kniha Probability Models for DNA Sequence Evolution Richard Durrett

Probability Models for DNA Sequence Evolution

Jazyk: Angličtina
Väzba: Pevná
Dostupnosť: Skladom u dodávateľa
Odosielame za 10-18 dní
192.55
As a starting point the authors address the fundamental question "What underlying forces are respons...

Informácie o knihe

Jazyk
Angličtina
Väzba
Kniha - Pevná
Vydalo
2008
Stránok
431
EAN
9780387781686
ISBN
0387781684
Enbook ID
01247776
Hmotnosť
614
Rozmery
164 x 244 x 30

Kompletný popis

As a starting point the authors address the fundamental question "What underlying forces are responsible for the observed patterns of variability, given a collection of DNA sequences?" In approaching this question they introduce and analyze a number of probability models: the Wright-Fisher model, the coalescent, the infinite alleles model, and the infinite sites model. They then discuss the complications that come from nonconstant population size, recombination, population subdivision, and three forms of natural selection: directional selection, balancing selection, and background selection. These theoretical results set the stage for the investigation of various statistical tests to detect departures from "neutral evolution."

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