Optimization in Drug Discovery

Name: Optimization in Drug Discovery
Brand: Humana Press Inc.
SKU: 9781627037419
Price: 194.71 EUR
Availability: InStock

In Vitro Methods

Autor: Gary W. Caldwell, Zhengyin Yan

Jazyk:

Väzba: Pevná

Vydavateľ: Humana Press Inc.

Dostupnosť: Skladom u dodávateľa

Odosielame za 10-13 dní

194.71 €

Thoroughly revised and updated, Optimization in Drug Discovery: In Vitro Methods, Second Edition pre...

Informácie o knihe

Autor

Gary W. Caldwell, Zhengyin Yan

Jazyk

Angličtina

Väzba

Kniha - Pevná

Vydalo

2013

Stránok

597

EAN

9781627037419

ISBN

1627037411

Enbook ID

02067260

Vydavateľ

Humana Press Inc.

Hmotnosť

1339

Rozmery

178 x 254 x 38

Kompletný popis

Thoroughly revised and updated, Optimization in Drug Discovery: In Vitro Methods, Second Edition presents a wide spectrum of in vitro assays including formulation, plasma binding, absorption and permeability, cytochrome P450 (CYP) and UDP-glucuronosyltransferases (UGT) metabolism, CYP inhibition and induction, drug transporters, drug-drug interactions via assessment of reactive metabolites, genotoxicity, and chemical and photo-mutagenicity assays. Written for the Methods in Pharmacology and Toxicology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Expert authors have developed and utilized these in vitro assays to achieve drug-like characteristics in addition to efficacy properties and good safety profiles of drug candidates.§Comprehensive and up-to-date, Optimization in Drug Discovery: In Vitro Methods, Second Edition aims to guide researchers down the difficult path to successful drug discovery and development.§

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Optimization in Drug Discovery

In Vitro Methods

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