Kniha Leucocyte Trafficking A. Hamann

Leucocyte Trafficking

The Role of Fucosyltransferases and Selectins

Jazyk: Angličtina
Väzba: Brožovaná
Dostupnosť: Skladom u dodávateľa v malom množstve
Odosielame za 11-15 dní
162.48
An essential component of inflammation is the migration of circulating leukocytes from blood into ti...

Informácie o knihe

Jazyk
Angličtina
Väzba
Kniha - Brožovaná
Vydalo
2013
Stránok
242
EAN
9783662053997
ISBN
3662053993
Enbook ID
02176289
Hmotnosť
339
Rozmery
148 x 14 x 15

Kompletný popis

An essential component of inflammation is the migration of circulating leukocytes from blood into tissues. This process is characterized by a multistep paradigm of sequential cell adhesion and activation events that lead to the extravasation of specific leukocyte subsets to different tissues in health and disease. The first step of leukocyte extravasation, the rolling of leukocytes, is primarily mediated by the interactions of selectins and their ligands. It has recently become evident that fucosyltransferases are crucial for selectin ligand synthesis, inflammation, and skin homing. This book provides an in-depth overview of the mechanisms of leukocyte trafficking and of the molecular mechanisms of selectin/selectin ligand interactions and discusses options for pharmacological intervention to treat inflammatory diseases.§

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