Kinase Screening and Profiling

Methods and Protocols

Autor: Said A. Goueli, Hicham Zegzouti

Jazyk:

Väzba: Brožovaná

Vydavateľ: Humana Press Inc.

Dostupnosť: Skladom u dodávateľa

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This volume focuses on screening and profiling kinase inhibitors or activators. Chapters in this boo...

Informácie o knihe

Autor

Said A. Goueli, Hicham Zegzouti

Jazyk

Angličtina

Väzba

Kniha - Brožovaná

Vydalo

2016

Stránok

223

EAN

9781493949236

ISBN

1493949233

Enbook ID

18049989

Vydavateľ

Humana Press Inc.

Hmotnosť

4511

Rozmery

178 x 254 x 13

Kompletný popis

This volume focuses on screening and profiling kinase inhibitors or activators. Chapters in this book cover several facets of the drug discovery processes starting with target identification, and assay development and screening chemical libraries for hit identification and lead optimization. The profiling portion of Kinase Screening and Profiling: Methods and Protocols discusses several strategies and techniques that are required to minimize off target hits and reduce cellular toxicities that are caused by liability kinases. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Timely and authoritative, Kinase Screening and Profiling: Methods and Protocols, will benefit scientists and researchers who are interested in exploring the role of kinases in academic, as well as pharmaceutical research.

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Kinase Screening and Profiling

Methods and Protocols

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