Intelligent Disulfide Connectivity Discovery

Name: Intelligent Disulfide Connectivity Discovery
Brand: LAP Lambert Academic Publishing
SKU: 9783659200793
Price: 42.46 EUR
Availability: InStock

Towards Protein 3D Structure Prediction

Autor: Monther Alhamdoosh

Jazyk:

Väzba: Brožovaná

Vydavateľ: LAP Lambert Academic Publishing

Dostupnosť: Skladom u dodávateľa

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42.46 €

The disulfide connectivity of a protein chain containing oxidized cysteines determines the pairing m...

Informácie o knihe

Autor

Monther Alhamdoosh

Jazyk

Angličtina

Väzba

Kniha - Brožovaná

Vydalo

2013

Stránok

120

EAN

9783659200793

Enbook ID

02208262

Vydavateľ

LAP Lambert Academic Publishing

Hmotnosť

197

Rozmery

150 x 220 x 7

Kompletný popis

The disulfide connectivity of a protein chain containing oxidized cysteines determines the pairing motif of these cysteines. This book aims at developing an intelligent system to predict the disulfide connectivity from solely the protein primary sequence. The book examines two different machine learning approaches to develop such systems: Neural Networks and Support Vector Machines. The book flows in five chapters that introduce the problem of disulfide connectivity prediction, thoroughly review the state-of-the-art researches, present our two-phase machine learning framework and technical details, and eventually investigate the performance of this intelligent system on real data from PDB database. This book, therefore, is step-by-step guide for researchers to develop intelligent systems that facilitate discovering disulfide connectivity patterns in protein chains. Moreover, researchers interested in the challenging problem of protein 3D structure prediction can benefit from this book to reduce the number of possible structural conformations of a given protein sequence and consequently obtain better understanding of protein folding.

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Intelligent Disulfide Connectivity Discovery

Towards Protein 3D Structure Prediction

Informácie o knihe

Kompletný popis

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