Immunological Synapse

Name: Immunological Synapse
Brand: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
SKU: 9783642038570
Price: 149.79 EUR
Availability: InStock

Autor: Takashi Saito, Facundo D. Batista

Jazyk:

Väzba: Pevná

Vydavateľ: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG

Dostupnosť: Skladom u dodávateľa

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While the importance of the immune synapse as a dynamic cell junction that regulates intercellular c...

Informácie o knihe

Autor

Takashi Saito, Facundo D. Batista

Jazyk

Angličtina

Väzba

Kniha - Pevná

Vydalo

2009

Stránok

255

EAN

9783642038570

ISBN

3642038573

Enbook ID

01650366

Vydavateľ

Springer-Verlag Berlin and Heidelberg GmbH & Co. KG

Hmotnosť

626

Rozmery

155 x 235 x 21

Kompletný popis

While the importance of the immune synapse as a dynamic cell junction that regulates intercellular communication and viral transmission is universally recognized, many of quantitative and qualitative details remain unsettled. The plasticity of this cell junction has to accommodate many very different binding partners and control the fate of interacting cells. It is likely that developmental changes in the state of the T cells or the APCs can impact the structure of the synapse. It is hoped that uncovering the ordered molecular rearrangement at the membrane will provide the long sought after clues for the remarkable functional sensitivity of T lymphocytes. These dynamic molecular interactions may eventually explain how engagement of the same TCR can generate different outcomes that resolve the immune challenges. The reviews in this issue present a broad slice of the many diverse topics that are currently intensely debated.

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