Kniha Hdac/Hat Function Assessment and Inhibitor Development: Methods and Protocols Oliver H. Krämer

Hdac/Hat Function Assessment and Inhibitor Development: Methods and Protocols

Jazyk: Angličtina
Väzba: Brožovaná
Vydavateľ: HUMANA PR
Dostupnosť: Skladom u dodávateľa
Odosielame za 5-8 dní
175.51
This fully updated edition provides a series of methods for how best to assess functions of histone...

Informácie o knihe

Jazyk
Angličtina
Väzba
Kniha - Brožovaná
Vydalo
2023
Stránok
511
EAN
9781071627907
ISBN
1071627902
Enbook ID
44302331
Vydavateľ
Hmotnosť
911

Kompletný popis

This fully updated edition provides a series of methods for how best to assess functions of histone deacetylases and acetyltransferases. The disease-relevance of dysregulated protein deacetylation by overexpressed or aberrantly activated histone deacetylases has spurred an intense search for novel and improved inhibitors of these enzymes, as reflected in this collection. Expert contributors explore the generation and evaluation of novel histone deacetylase inhibitors and new and improved techniques to assess acetylation-dependent molecular mechanisms in vitro and in vivo. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 
Authoritative and up-to-date, HDAC/HAT Function Assessment and Inhibitor Development: Methods and Protocols, Second Edition serves as an ideal guide for researchers seeking to further elucidate this vital area of study.

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