GnRH Neuron and its Control

Autor: Allan E. Herbison, Tony M. Plant

Jazyk:

Väzba: Pevná

Vydavateľ: John Wiley and Sons Ltd

Dostupnosť: Skladom u dodávateľa v malom množstve

Odosielame za 11-15 dní

164.07 €

The GnRH Neuron and its Control examines the developmental biology of GnRH neurons including their b...

Informácie o knihe

Autor

Allan E. Herbison, Tony M. Plant

Jazyk

Angličtina

Väzba

Kniha - Pevná

Vydalo

2018

Stránok

536

EAN

9781119233244

ISBN

9781119233244

Enbook ID

18318864

Vydavateľ

John Wiley and Sons Ltd

Hmotnosť

1070

Rozmery

250 x 178 x 28

Kompletný popis

The GnRH Neuron and its Control examines the developmental biology of GnRH neurons including their birth in the nasal placode of the early embryo, perinatal programming, and sexual differentiation, in addition to the hypothalamic mechanisms that control GnRH neurons in adulthood to generate pulsatile and surge modes of GnRH secretion throughout the major life stages including aging. The morphology, electrophysiology, signal transduction pathways, transcriptional regulators, and genomics underlying function of the adult GnRH neuron is discussed in detail, as is the neuroendocrinology and cell biology governing the generation of both modes of GnRH release. The book also reviews the neurobiological mechanisms and circuitry responsible for the modulation of the activity of GnRH neurons by season, stress, nutrition, and metabolism, and covers the current and potential therapeutic approaches to regulating GnRH secretion and action. Filled with newly identified research and classical fundamental knowledge to GnRH biology, it will provide students, researchers, and practitioners with an in-depth understanding of reproductive neuroendocrinology. This is the fifth volume in the Masterclass in Neuroendocrinology Series, a co- publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.

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