Gene Selection Based on Consistency Modelling, Algorithms and Applications - Genetic Algorithm Application in Bioinformatics Data Analysis

Name: Gene Selection Based on Consistency Modelling, Algorithms and Applications - Genetic Algorithm Application in Bioinformatics Data Analysis
Brand: VDM Verlag Dr. Mueller E.K.
SKU: 9783639008838
Price: 47.53 EUR
Availability: InStock

Autor: Yingjie Hu

Jazyk:

Väzba: Brožovaná

Vydavateľ: VDM Verlag Dr. Mueller E.K.

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Consistency modeling for gene selection is a new topicemerging from recent cancer bioinformatics res...

Informácie o knihe

Autor

Yingjie Hu

Jazyk

Angličtina

Väzba

Kniha - Brožovaná

Vydalo

2008

Stránok

112

EAN

9783639008838

ISBN

3639008839

Enbook ID

06810963

Vydavateľ

VDM Verlag Dr. Mueller E.K.

Hmotnosť

159

Rozmery

152 x 229 x 6

Kompletný popis

Consistency modeling for gene selection is a new topicemerging from recent cancer bioinformatics research. The result ofclassification or clustering on a training set was often found verydifferent from the same operations on a testing set. Here, theissue is addressed as a consistency problem. In practice, theinconsistency of microarray datasets prevents many typical geneselection methods working properly for cancer diagnosis andprognosis. In an attempt to deal with this problem, a new conceptof performance-based consistency is proposed in this thesis. Theproposed consistency concept has been investigated on eightbenchmark microarray and proteomic datasets. The experimentalresults show that the different microarray datasets have differentconsistency characteristics, and that better consistency can leadto an unbiased and reproducible outcome with good diseaseprediction accuracy.

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Gene Selection Based on Consistency Modelling, Algorithms and Applications - Genetic Algorithm Application in Bioinformatics Data Analysis

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