Gamete Proteomics

Name: Gamete Proteomics
Brand: LAP Lambert Academic Publishing
SKU: 9783659243356
Price: 42.46 EUR
Availability: InStock

Analysis of the human sperm proteome

Autor: Søren Naaby-Hansen

Jazyk:

Väzba: Brožovaná

Vydavateľ: LAP Lambert Academic Publishing

Dostupnosť: Skladom u dodávateľa

Odosielame za 5-8 dní

42.46 €

This book reviews a series of functional and immunological studies of the human sperm proteome. Two...

Informácie o knihe

Autor

Søren Naaby-Hansen

Jazyk

Angličtina

Väzba

Kniha - Brožovaná

Vydalo

2012

Stránok

116

EAN

9783659243356

Enbook ID

07023393

Vydavateľ

LAP Lambert Academic Publishing

Hmotnosť

189

Rozmery

150 x 220 x 7

Kompletný popis

This book reviews a series of functional and immunological studies of the human sperm proteome. Two of the most cited studies originate from the examination of capacitation-induced protein modifications, which led to the cloning and characterisation of two new phospho-regulated cancer-testis antigens, named AKAP3 and CABYR. AKAP3 is a member of the A kinase anchoring protein-family, which provides spatial and temporal specificity to the cAMP-PKA pathway. In addition to scaffolding PKA, PDE and protein phosphatases, AKAP members also bind proteins that share homology to the RII dimerization/docking (R2D2) domain of PKA regulatory subunit. CABYR likewise interacts with a diverse array of signal tranducer molecules via its SH3-, R2D2-, and proline-rich extension-like domains. AKAP3 and CABYR associate in high molecular weight multi-protein complexes, which appear to regulate the energy supply to and motion of the sperm flagellum. The putative functional role of the CABYR signalling scaffold in cancer cells is discussed.

Mohlo by vás zaujímať

Zákazníci, ktorí si kúpili túto knihu, kúpili tiež

Najčastejšie vyhľadávané

Categories

Authors

Publishers

Produkty

Produkty

Najčastejšie vyhľadávané

Categories

Authors

Publishers

Produkty

Produkty

Gamete Proteomics

Analysis of the human sperm proteome

Informácie o knihe

Kompletný popis

Mohlo by vás zaujímať

Zákazníci, ktorí si kúpili túto knihu, kúpili tiež