Endotoxins: Structure, Function and Recognition

Name: Endotoxins: Structure, Function and Recognition
Brand: Springer
SKU: 9789048190775
Price: 199.2 EUR
Availability: InStock

Autor: Xiaoyuan Wang, Peter J. Quinn

Jazyk:

Väzba: Pevná

Vydavateľ: Springer

Dostupnosť: Skladom u dodávateľa

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199.20 €

Endotoxins are potentially toxic compounds produced by Gram-negative bacteria including some pathoge...

Informácie o knihe

Autor

Xiaoyuan Wang, Peter J. Quinn

Jazyk

Angličtina

Väzba

Kniha - Pevná

Vydalo

2010

Stránok

415

EAN

9789048190775

ISBN

9048190770

Enbook ID

01976746

Vydavateľ

Springer

Hmotnosť

896

Rozmery

155 x 235 x 31

Kompletný popis

Endotoxins are potentially toxic compounds produced by Gram-negative bacteria including some pathogens. Unlike exotoxins, which are secreted in soluble form by live bacteria, endotoxins are comprised of structural components of bacteria. §Endotoxins can cause a whole-body inflammatory state, sepsis, leading to low blood pressure, multiple organ dysfunction syndrome and death.§This book brings together contributions from researchers in the forefront of these subjects. It is divided into two sections: the first dealing with how endotoxins are synthesized and end up on the bacterial surface. The second discussed how endotoxins activate the Toll-like receptor TLR4 and, in turn, how TLR4 generates the molecular signals leading to infectious and inflammatory diseases.§The way endotoxins interact with the host cells is fundamental to understanding the mechanism of sepsis, and recent research on these aspects of endotoxins has served to illuminate previously undescribed functions of the innate immune system. This volume presents a description of endotoxins according to their genetic constitution, structure, function and mode of interaction with host cells.

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Endotoxins: Structure, Function and Recognition

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