Complement Activation in Malaria Immunity and Pathogenesis

Name: Complement Activation in Malaria Immunity and Pathogenesis
Brand: Springer International Publishing AG
SKU: 9783319772578
Price: 99.98 EUR
Availability: InStock

Autor: José A. Stoute

Jazyk:

Väzba: Pevná

Vydavateľ: Springer International Publishing AG

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Plasmodium falciparum malaria is responsible for the deaths of nearly 500,000 people each year. Much...

Informácie o knihe

Autor

José A. Stoute

Jazyk

Angličtina

Väzba

Kniha - Pevná

Vydalo

2018

Stránok

149

EAN

9783319772578

ISBN

3319772570

Enbook ID

18942959

Vydavateľ

Springer International Publishing AG

Hmotnosť

418

Rozmery

155 x 235 x 14

Kompletný popis

Plasmodium falciparum malaria is responsible for the deaths of nearly 500,000 people each year. Much attention has been paid to antibody and cellular mechanisms of immunity against this pathogen. By contrast, the role that the complement system plays in immunity and pathogenesis in this infection is not very well recognized or understood. Based on the work of a number of research groups, we know that complement plays an important role in these processes. In this book, some of the leading scientists in the field discuss the mechanisms of complement activation during malaria infection as well as the role of complement in the pathogenesis of key syndromes such as severe malarial anemia, cerebral malaria, and placental malaria. In addition, they review recently-identified complement evasion strategies of P. falciparum merozoites, and how these mechanisms may translate into paradoxical enhancement of infection rather than protection. Finally, they also discuss the role of the mosquito complement system on immunity against the parasite.

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Complement Activation in Malaria Immunity and Pathogenesis

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