Catalytically Active Nucleic Acids

Name: Catalytically Active Nucleic Acids
Brand: Springer Nature Switzerland AG
SKU: 9783030296483
Price: 205.35 EUR
Availability: InStock

Autor: Johanna-Gabriela Walter, Frank Stahl

Jazyk:

Väzba: Brožovaná

Vydavateľ: Springer Nature Switzerland AG

Dostupnosť: Skladom u dodávateľa

Odosielame za 10-18 dní

205.35 €

This volume reviews numerous reaction mechanisms and applications of nucleic acids with catalytic ac...

Informácie o knihe

Autor

Johanna-Gabriela Walter, Frank Stahl

Jazyk

Angličtina

Väzba

Kniha - Brožovaná

Vydalo

2020

Stránok

123

EAN

9783030296483

ISBN

3030296482

Enbook ID

33286556

Vydavateľ

Springer Nature Switzerland AG

Hmotnosť

215

Rozmery

155 x 235 x 8

Kompletný popis

This volume reviews numerous reaction mechanisms and applications of nucleic acids with catalytic activity. Written by an interdisciplinary team of authors, it provides an essential overview of these acids' fundamental aspects, while also addressing associated methodologies such as nucleic acid enzyme engineering, peroxidase-mimicking DNAzymes and Aptazymes.After the discovery of natural ribozymes - RNA molecules that mediate the cleavage and formation of phosphodiester bonds and the formation of peptide bonds - numerous artificial ribozymes with altered catalytic activities were produced by in vitro and in vivo selection. Unlike ribozymes, DNAzymes do not occur in nature. Although the catalytic activity of nucleic acid enzymes is usually much slower than that of proteins, nucleic acid enzymes with comparable catalytic activity have been obtained using stringent selection processes. The key advantages of these enzymes: they are e.g. smaller, easier to produce and purify than proteins, and can withstand denaturation, e.g. by heat.Over the last few years, the number of publications on the applications of enzymatic nucleic acids has grown steadily. Summarizing the fundamentals and applications of these acids, this book will not only be an excellent resource for experts in the field but will also guide young researchers just starting out in this significant area.

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