Bismuth-Ethanedithiol

A Potential Drug to Treat Biofilm Infections of Medical Devices Produced by Staphylococcus Epidermidis and Proteus Mirabilis

Autor: Jithendra Gunawardana

Jazyk:

Väzba: Brožovaná

Vydavateľ: Dissertation.com

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Staphylococcus epidermidis is the leading cause of hospital-acquired infections associated with impl...

Informácie o knihe

Autor

Jithendra Gunawardana

Jazyk

Angličtina

Väzba

Kniha - Brožovaná

Vydalo

2010

Stránok

EAN

9781599423043

ISBN

9781599423043

Enbook ID

08765691

Vydavateľ

Dissertation.com

Hmotnosť

191

Rozmery

189 x 246 x 5

Kompletný popis

Staphylococcus epidermidis is the leading cause of hospital-acquired infections associated with implanted medical devices. Likewise, Proteus mirabilis is one of the leading causes of nosocomial Urinary Tract Infections (UTIs) and is associated with urinary catheter blockage. Both organisms produce biofilms, which make them less susceptible to antibiotics. Therefore, these infections are often notoriously difficult to treat and in many cases lead to complications. Preventing biofilm formation or killing a pre-existing biofilm would be useful solutions since biofilm formation is a phenomenon commonly observed in these organsims. This study investigated the in vitro efficacy of Bismuth-ethanedithiol (BisEDT) against biofilms produced by P. mirabilis and S. epidermidis. Anti-biofilm activity of BisEDT was evaluated in terms of inhibiting/preventing biofilm formation and eradicating/killing pre-formed biofilm produced by single species S. epidermidis and P. mirabilis.

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Bismuth-Ethanedithiol

A Potential Drug to Treat Biofilm Infections of Medical Devices Produced by Staphylococcus Epidermidis and Proteus Mirabilis

Informácie o knihe

Kompletný popis

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Zákazníci, ktorí si kúpili túto knihu, kúpili tiež