Kniha Bioreactor Processes Based on Disposable Materials Matthieu Stettler

Bioreactor Processes Based on Disposable Materials

for the production or recombinant proteins from mammalian cells

Jazyk: Angličtina
Väzba: Brožovaná
Vydavateľ: VDM Verlag
Dostupnosť: Skladom u dodávateľa
Odosielame za 9-15 dní
56.90
The objective of industrial cell culture technology is to produce high value-added therapeutic prote...

Informácie o knihe

Jazyk
Angličtina
Väzba
Kniha - Brožovaná
Vydalo
2009
Stránok
152
EAN
9783639150285
ISBN
3639150287
Enbook ID
06823570
Vydavateľ
Hmotnosť
242
Rozmery
151 x 229 x 9

Kompletný popis

The objective of industrial cell culture technology is to produce high value-added therapeutic proteins that are well suited for the treatment of infectious diseases, cancer, and autoimmune diseases. Nowadays, an important focus is the reduction of the time and costs from the discovery of the candidate molecule to the full-scale production. Relying on enabling technologies is critical for meeting this objective. Simultaneously, novel technologies are expected to increase the clinical and commercial success rates. In recent years, new concepts based on innovative disposable materials emerged and appeared to be promising alternatives to standard bioprocessing equipment. This thesis work focused on the development of such disposable compounds in mammalian cell culture applications, particularly for the containment of the cells, and was aimed at demonstrating their benefit in terms of cost- effectiveness, ease-of-use and flexibility. Most importantly, it established that orbital shake technology can be used for a wide range of operating scales, from only a few milliliters for optimization purposes up to production scale.

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