Antifungals

Name: Antifungals
Brand: Caister Academic Press
SKU: 9781910190012
Price: 219.72 EUR
Availability: InStock

From Genomics to Resistance and the Development of Novel Agents

Autor: Alix T Coste, Patrick Vandeputte

Jazyk:

Väzba: Pevná

Vydavateľ: Caister Academic Press

Dostupnosť: Skladom u dodávateľa

Odosielame za 9-15 dní

219.72 €

Infections caused by pathogenic fungi are a significant global problem, a situation exacerbated by t...

Informácie o knihe

Autor

Alix T Coste, Patrick Vandeputte

Jazyk

Angličtina

Väzba

Kniha - Pevná

Vydalo

2015

Stránok

344

EAN

9781910190012

ISBN

1910190012

Enbook ID

12484083

Vydavateľ

Caister Academic Press

Hmotnosť

1062

Rozmery

254 x 183 x 29

Kompletný popis

Infections caused by pathogenic fungi are a significant global problem, a situation exacerbated by the limited availability of good antifungal options. Being eukaryotic organisms, these pathogens are phylogenetically much closer to the human host than bacterial pathogens. This sets serious limits to the range of exploitable fungal-specific drug targets. The advent of 'omics' and other high throughput technologies in recent years has revolutionized the field of antifungal research permitting researchers to quickly identify novel compounds and gain greater insights into drug resistance mechanisms. Researchers can analyze the whole organism's response to any particular condition or compound, thereby providing a deeper understanding of fungal biology and the host-fungus interaction. In this book, a panel of high-profile contributors provides an overview of current antifungal research. Chapters are written from a molecular and genomic perspective and contain speculative models upon which to base future research efforts. Topics include: the molecular mechanisms responsible for antifungal resistance to the classical molecules, azoles, polyenes, and echinocandins * fungal biofilms * fungal-specific biological pathways that constitute potential new targets * strategy to potentiate existing antifungal agents * impact of high throughput screenings of chemical compound collections * modulating the host response * antifungal vaccines * animals models. The book will be an essential reference for everyone with an interest in fungal pathogenesis. It is recommended for all biology and medical libraries. [Subject: Molecular Biology, Genomics, Life Science

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Antifungals

From Genomics to Resistance and the Development of Novel Agents

Informácie o knihe

Kompletný popis

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