Refractory Celiac Disease

1. Introduction.- 2. Pathogenesis of refractory celiac disease (I): role of virus and microbiota.- 3.Pathogenesis of refractory celiac disease (II): from refractory celiac disease to overt lymphoma.- 4. Pathogenesis of refractory celiac disease (III): genetic basis.-5. From unresponsive celiac disease to refractory celiac disease.- 6. Epidemiology of refractory celiac disease.- 7. Diagnosis of refractory celiac disease: Isolation-flow phenotyping and clonality.- 8.Diagnosis of refractory celiac disease: pathology.- 9. The other causes of severe enteropathy with villous atrophy non responsive to a gluten free diet.- 10.Treatment of Refractory Celiac disease.