Gene, Drug, and Tissue Engineering

Part I: Molecular Genetics and Genomics

1. Gene Alterations Induced by Glutamine (Q) Encoding CAG Repeats Associated with Neurodegeneration

Gundappa Saha, Sukanya Ghosh, Vikash Kumar Dubey, and Prakash Saudagar

Glaucia C. Pereira

3. Nanotechnology Driven Delivery Systems in Inoculation Therapies

Glaucia C. Pereira

Part II: Molecular Biology in Drug Development and Therapeutics

4. Chronic Kidney Disease: Challenges in Translational Medicine

Bruno Freire Botelho, Andr Luis Barreira, Maurilo Leite Jr., and Marcelo Marcos Morales

5. Mass Spectroscopy as an Analytical Tool to Harness the Production of Secondary Plant Metabolites: The Way Forward for Drug Discovery

Faheem Ahmad and Hera Nadeem

6. Assessing the Challenges of Nanotechnology-Driven Targeted Therapies: Development of Magnetically Directed Vectors for Targeted Cancer Therapies and Beyond

Matthew T. Bryan

Part III: Molecular, Cellular, Tissue Engineering, and AI-Based Computational Design

7. Advances in Regenerative Medicine and Biomaterials

Ş
kran Ş
eker, Ayş
e Eser Elin, and Yaş
ar Murat Elin

8. A Brief Review of Plant Cell Transfection, Gene Transcript Expression, and Genotypic Integration for Enhancing Compound Production

Munish Sharma, Sakshi Bhushan, Deepak Sharma, Sanjana Kaul, and Manoj K. Dhar

9. A Review of Stem Cell Technology Targeting Hepatocyte Growth as an Alternative to Organ Transplantation

Ernesto Goulart

10. Novel Nanotechnology-Driven Prototypes for AI-Enriched Implanted Prosthetics Following Organ Failure

Glaucia C. Pereira

Part IV: Methods and Protocols

11. Simplified CRISPR-Mediated DNA Editing in Multicellular Eukaryotes

Ritesh Kumar, Kartikeya Tiwari, and Prakash Saudagar

12. Design of SaCas9-HF for In Vivo Gene Therapy

Kartikeya Tiwari, Ritesh Kumar, and Prakash Saudagar

13. Stem Cell Technology in Organ Transplantation: A Novel Method for 3D Bioprinting Functional and Stable Liver Grafts Using Human iPS-Derived Cells

Ernesto Goulart

14. In Vitro Assay for the Assessment of Oxygen Depletion Triggers in Human Cell Lines, Associated with Improving Responses to Cancer Therapy

Kartikeya Tiwari, Ritesh Kumar, Gundappa Saha, and Prakash Saudagar

15. The Use of ^99mTc-Labeled Stem Cells for Evaluat