Human Reproductive and Prenatal Genetics

Recent advances in genetic testing and prenatal screening have revolutionized the practice of reproductive medicine, obstetrics, gynecology, andrology, and infertility treatment. With Human Reproductive and Prenatal Genetics, editors Peter Leung and Jie Qiao have compiled the most comprehensive, practical reference title available for researchers, clinicians, and students seeking the latest applied knowledge and clinical techniques in these fields. Chapter contributions from leading scientists and clinicians provide in-depth, application-driven coverage of key topics in human reproductive and prenatal genetics, including genetic control underlying the development of the reproductive tracts and gametogenesis, the genetics of fertilization and implantation, the genetic basis of female and male infertility, as well as genetic and epigenetic aspects of assisted reproduction. Also examined in detail are the genetics and epigenetics of the placenta in normal and abnormal pregnancy
preimplantation genetic diagnosis and screening, with special attention to cutting-edge advances in noninvasive prenatal screening
prenatal genetic counseling
and bioethical and medicolegal aspects of relevance in the lab and clinic.

This Second Edition has been fully revised to address new and evolving technologies in human reproductive genetics, with new chapters added on chromatin landscapes and sex determination, genetic alterations of placental development and preeclampsia, metabolism and inflammation in PCOS, pre-implantational genetic testing, maternal genetic disorders, bioethics, and future applications.